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US Peptide Guide
Updated May 2026 · 7 peptides indexed

The evidence behind every peptide.

A vendor-neutral, citation-dense reference for peptide therapies. Every claim sourced. Evidence graded on a four-tier scale. Reviewed against current FDA compounding status.

What this is
  • Every claim linked to a numbered source — PubMed, FDA documents, or named experts with dates.
  • Animal data, case reports, and human RCTs separated — never blended.
  • Regulatory status with a specific effective date on every page.
What this is not
  • No dosing protocols. Dosing decisions belong with a licensed prescriber.
  • No vendor recommendations on reference pages.
  • Not medical advice. Not a substitute for clinical judgment.

The four-tier evidence framework

Methodology →

Applied consistently across every page so you can compare peptides on the same scale, not on marketing claims.

Tier 1
FDA-Approved

Completed Phase 3 trials, FDA approval for at least one indication.

Tier 2
Clinically Studied

Multiple human RCTs (n>50 total), available through licensed compounding.

Tier 3
Limited Human Evidence

Some published human data (case reports, small studies), strong animal data.

Tier 4
Animal Data Only

No published human trials. Mechanism inferred from animal models.

Recently updated

View all 7 entries
Active regulatory event
14 peptides returned to Category 1 status on April 23, 2026.
Final review at the Pharmacy Compounding Advisory Committee meeting, July 23–24, 2026.
See the timeline